Khang thuoc Botulinum Toxin — Thu thuat tham my co thuc su an toan? Hay suy nghi lai

“Cac thu thuat tham my hoan toan khong mien dich voi tinh trang khang botulinum toxin.”

Tien si Kyle Seo, M.D., Ph.D., Nguoi sang lap Modelo Clinic va la nguoi tien phong the he dau tien ve lieu phap botulinum toxin (toxin) tai Han Quoc, da dua ra canh bao nghiem tuc. Khi pham vi ung dung cua toxin khong ngung mo rong tu cai thien nep nhan sang nhieu vung co the khac, nguy co khang thuoc do tiem lieu cao lap lai khong con co the xem nhe.

De chung minh dieu nay bang du lieu khach quan, tu nam 2014 Tien si Seo da he thong thu thap cac ca nghi ngo khang thuoc tren thuc te lam sang. Qua kiem tra khang thuoc lam sang va xet nghiem mau, ong xac nhan khang thuoc o toi 80 benh nhan.

■Tien si Kyle Seo xac nhan bo du lieu khang thuoc tham my lon nhat the gioi

Tien si Seo du kien cong bo nghien cuu nay duoi dang bai bao khoa hoc trong nua cuoi nam nay. Day duoc ky vong la bao cao du lieu khang botulinum toxin lon nhat trong linh vuc y hoc tham my tren toan cau, va co the tao ra canh bao manh me cho ca gioi lam sang lan nganh tham my. Cho den nay, hau het cac bao cao khang thuoc trong linh vuc tham my chi dua tren phan tich mot so it ca benh.

"Toi cho rang can co bang chung khach quan, co the do luong duoc moi co the thuc su nang cao nhan thuc ve khang toxin," Tien si Seo giai thich. "Trong so 80 benh nhan, 35 nguoi duoc xet nghiem mau de kiem tra su hien dien cua khang the trung hoa — yeu to lien quan truc tiep den khang thuoc — qua do tang cuong tinh khach quan cua du lieu."

■Tiem lieu cao lap lai va protein phuc hop thuc day khang thuoc

Phan tich cac ca khang thuoc cho thay tong lieu tich luy tu viec tiem lieu cao lap lai la yeu to chinh lam tang nguy co khang thuoc. Su hien dien cua protein phuc hop trong che pham cung duoc xac dinh la co anh huong.

"O nhung benh nhan chuyen sang che pham toxin thuan khiet — loai da loai bo protein phuc hop — khong ghi nhan them bat ky ca khang thuoc nao," Tien si Seo luu y.

■Khang thuoc tham my de doa cac dieu tri benh ly quan trong trong tuong lai

Tien si Seo nhieu lan nhan manh rang tinh trang khang thuoc phat sinh tu cac thu thuat tham my co the gay he qua nghiem trong cho viec dieu tri cac benh ly sau nay. Botulinum toxin duoc su dung de dieu tri nhieu benh nhu co giat nua mat, loan truong luc co co va co cung sau dot quy. Mot khi khang the trung hoa hinh thanh, chung luu thong toan than va lam giam hieu qua cua toxin tren tat ca cac chi dinh dieu tri.

"Khang thuoc khong chi lam giam hieu qua tham my — no con co the thu hep lua chon dieu tri benh bang toxin trong tuong lai. Phong ngua ngay tu dau la dieu quan trong nhat," Tien si Seo nhan manh.

"Khang thuoc khong chi lam giam hieu qua tham my — no con co the thu hep lua chon dieu tri benh bang toxin trong tuong lai. Phong ngua ngay tu dau la dieu quan trong nhat," Tien si Seo nhan manh.

■Phong ngua bat dau tu khoang cach tiem va lua chon che pham

Khang thuoc co the duoc giam thieu dang ke bang cach duy tri khoang cach toi thieu 3 thang giua cac lan tiem va tranh tiem lieu cao hoac lap lai khong can thiet. Lua chon che pham toxin thuan khiet khong chua protein phuc hop cung la bien phap khon ngoan. Benh nhan nhan thay hieu qua khong con keo dai nhu truoc nen tam dung dieu tri va thong bao trung thuc cho bac si.

"Nghien cuu nay se nang cao canh giac ve viec tiem lieu cao lap lai va dan den cac tieu chuan cu the hon ve lua chon che pham va quan ly khoang cach tiem. Quan niem rang thu thuat tham my an toan truoc khang botulinum toxin — da den luc phai tu bo suy nghi do."

1. Duy tri khoang cach tiem 3 thang: Botulinum toxin la che pham protein co kha nang gay phan ung mien dich. Tiem lap lai trong vong 2 tuan den 1 thang co the tao ra hieu ung tang cuong khang nguyen. Nen tranh tiem lap lai trong vong 1 thang bat cu khi nao co the.

2. Quan ly thong nhat khoang cach tiem tat ca cac vung: Du tiem o vung khac nhau, mien la su dung cung mot loai botulinum toxin, phoi nhiem khang nguyen van tich luy. Can quan ly toan bo lich tiem theo tieu chuan khoang cach 3 thang. (Nep nhan: moi 3-4 thang, 2 lan/nam; thon ham: moi 6-12 thang, 1 lan/nam.)

3. Than trong voi cac thu thuat lieu cao: Cac thu thuat co lieu tiem lon trong mot lan nhu thon ham, thon bap chan, vai thon nen duoc tiep can than trong ngay tu dau, voi tan suat va khoang cach duoc dieu chinh can than.

4. Chon che pham co nguy co khang thuoc thap hon: Che pham toxin thuan khiet da loai bo protein phuc hop kich thich phan ung mien dich, mang lai nguy co khang thuoc thap hon.